It has been designed by James F. Stephen, an architectural firm which has already been responsible for the design of two churches in the East of Scotland and which has been instrumental in redesigning the Royal Scots College in Salamanca. The main architect with the responsibility for the construction of the Chapel was Karl Pedersen, who supervised the work from an early stage.

The main features of the Chapel are its barrel vaulted ceiling and glass walls, which, in creating a strong sense of space, engender the feeling that the Chapel is at one with its surroundings. The sense of space is felt also in the large gallery, which has a large window following the line of the barrel vault. This area is available to the college community as an additional space for prayer and for meeting. The Chapel is fully geared to the needs of the disabled.

The fourteen stained glass panels representing the Stations of the Cross are by Ms. Shona McInnes of Bunhervie and have been commissioned for the College.

The tabernacle, the sanctuary lamp, the processional cross and the candlesticks were commissioned from Mr. John Creed, who designed the chalice and the paten for the Papal Mass at Bellahouston in 1982. Again specifically commissioned for the College, they reflect a motif from the 7th and 8th century Lindisfarne Gospels. These pieces are a combination of that history and twentieth century design. The decorated shafts of the Cross and Candlesticks echo the work of the Celts with their use of spirals. The materials used give visual and practical strength: the hot forged mild steel allows subtle nuances of shape such as the thickening of the ends. The twisting of the hexagonal bar of their shafts gives a repeat pattern, which is tactile and pleasant to hold. The steel is finished with renaissance wax and in parts bright polished. These traditional blacksmithing techniques are complemented by those of silversmithing where brass, plated with 22 carat gold, is used to give linear accent, volume and colour as with the knops of the shafts and cups of the candlesticks. The coloured glass spheres in the head of the Cross represent five Scottish saints: St Andrew - blue; St. Ninian - purple; St Columba - white; St. Mungo - green and St. Margaret gold.

The Presidential Chair, designed and crafted by Mr. J. McNally, is contoured to harmonize with the barrel-vaulted ceiling of the Chapel. The design featured on the chair, carved in cherry wood, is reminiscent of the processional cross design, again reflecting the Lindisfarne Gospels. The Presider's chasuble, which has also been designed to reflect the processional cross, was made by the sewing guild of St. Teresa's Church, Possilpark, Glasgow. With a view to emphasising the fact that Christ is present in his Word in the Eucharist celebrated and in the reserved sacrament, the ambo, the altar and the surround for the tabernacle were cut from a single piece of sandstone from a quarry in St. Andrew's in Fife.